POST api/PregnancyAndLactationInfoByDiagnosis

Provides the clinician with information about drugs indicated for a particular disease or condition for those females of childbearing age who may be pregnant and/or lactating.

Returns drug compatibility data for the supplied disease indication based on the following pregnancy and lactation category conditions:
  • Pregnancy (data includes FDA trimester ratings)
  • Lactation (data identifies drugs to avoid or use with caution; optionally returns lactation alternative drug therapies)
  • Labor and Delivery
  • Childbearing Age
Returns Level of Evidence documentation for off-label (non FDA approved) indications within select therapeutic classes (if available). Returns the associated Gold Standard Professional Drug Monograph “Pregnancy/Breast-feeding” section identifier for the drug, if applicable.


Request Information

URI Parameters

None.

Body Parameters

PregnancyAndLactationInfoByDiagnosisRequest
NameDescriptionTypeAdditional information
IndicationCodes A collection of diagnosis or indication codes to retrieve the pregnancy and lacatation information for. Collection of ConditionIdentifier

Required

LabelStatus Identifies whether to include on-label (FDA-approved) or off-label (non-FDA-approved) drugs in the response for the supplied indication codes. If no value is included in the request, then the method returns information for both on- and off-label drugs. LabelStatusEnum

None.

DateOfBirth The GSDD API converts the DateOfBirth value into an age and then matches to an age group. In GSDD, childbearing age (CBA) is defined as female gender with an age range of 13-50 years. If the DateOfBirth value indicates that the age is not within the childbearing age range, then the method returns the following message: “Input age is not a Child Bearing Age.” If no value is entered, the method returns all possible results for all pregnancy and lactation categories. date

None.

FilterBy Provides option to filter search results by pregnancy and lactation categories. If no value is included in the request, then the method returns information for all pregnancy and lactation categories. PregnancyAndLactationEnum

None.

Trimester The numeric pregnancy trimester number. If no value is included in the request, then the method returns information for all pregnancy trimesters. TrimesterEnum

None.

AccessToken Temporary access token from the GSDD Auth API. Used to validate your license.

Note: Access tokens are temporary and may be invalidated early for various reasons, including—but not limited to—site maintenance and security updates. If a token is invalidated prematurely, simply request new tokens via the AccessToken method in the GSDD Auth API. This is a rather rare occurrence, but should be planned for and handled by the consuming application.
string

Required

Request Formats

application/json, text/json

Sample:
{
  "IndicationCodes": [
    {
      "IdType": "ICD10",
      "Id": "123ABC1"
    },
    {
      "IdType": "ICD10",
      "Id": "123ABC2"
    }
  ],
  "LabelStatus": "OnLabel",
  "DateOfBirth": "2024-05-18",
  "FilterBy": "ChildBearingAge",
  "Trimester": "First",
  "AccessToken": "T25lX0hhcHB5X0FuZF9TYXRpc2ZpZWRfR1NERF9DdXN0b21lcl9TYW1wbGVfQWNjZXNzVG9rZW4="
}

Response Information

Resource Description

PregnancyAndLactationInfoByDiagnosisResponse
NameDescriptionTypeAdditional information
Diagnosis A collection of drug pregnancy and lactation rating information by diagnoses. Collection of PregnancyAndLactationConditionDrugRatings

Required

Response Formats

application/json, text/json

Sample:
{
  "Diagnosis": [
    {
      "Diagnosis": {
        "ConditionId": {
          "IdType": "ICD10",
          "Id": "123ABC1"
        },
        "Description": "Sample Description text.",
        "InfoMessage": "Sample InfoMessage text.",
        "LevelsOfEvidence": [
          {
            "Recommended": true,
            "StrengthOfRecommendation": "EquivocalWeakAgainst",
            "Rating": "VeryLow",
            "ErrorMessage": "Sample ErrorMessage text."
          },
          {
            "Recommended": true,
            "StrengthOfRecommendation": "EquivocalWeakAgainst",
            "Rating": "VeryLow",
            "ErrorMessage": "Sample ErrorMessage text."
          }
        ]
      },
      "Drugs": [
        {
          "Drug": {
            "DrugId": {
              "IdType": "NDC11",
              "Id": "12345-6789-02"
            },
            "Name": "Sample Name text.",
            "LevelsOfEvidence": [
              {
                "Recommended": true,
                "StrengthOfRecommendation": "EquivocalWeakAgainst",
                "Rating": "VeryLow",
                "ErrorMessage": "Sample ErrorMessage text."
              },
              {
                "Recommended": true,
                "StrengthOfRecommendation": "EquivocalWeakAgainst",
                "Rating": "VeryLow",
                "ErrorMessage": "Sample ErrorMessage text."
              }
            ],
            "Message": "Sample Message text."
          },
          "Ratings": [
            {
              "PregnancyAndLactationCategory": "ChildBearingAge",
              "Code": "Sample Code text.",
              "AlternateDrugs": [
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-03"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                },
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-04"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                }
              ],
              "Description": "Sample Description text.",
              "Trimester": "First",
              "MonographSectionId": 5,
              "InfoMessage": "Sample InfoMessage text."
            },
            {
              "PregnancyAndLactationCategory": "ChildBearingAge",
              "Code": "Sample Code text.",
              "AlternateDrugs": [
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-06"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                },
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-07"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                }
              ],
              "Description": "Sample Description text.",
              "Trimester": "First",
              "MonographSectionId": 8,
              "InfoMessage": "Sample InfoMessage text."
            }
          ],
          "InfoMessage": "Sample InfoMessage text."
        },
        {
          "Drug": {
            "DrugId": {
              "IdType": "NDC11",
              "Id": "12345-6789-00"
            },
            "Name": "Sample Name text.",
            "LevelsOfEvidence": [
              {
                "Recommended": true,
                "StrengthOfRecommendation": "EquivocalWeakAgainst",
                "Rating": "VeryLow",
                "ErrorMessage": "Sample ErrorMessage text."
              },
              {
                "Recommended": true,
                "StrengthOfRecommendation": "EquivocalWeakAgainst",
                "Rating": "VeryLow",
                "ErrorMessage": "Sample ErrorMessage text."
              }
            ],
            "Message": "Sample Message text."
          },
          "Ratings": [
            {
              "PregnancyAndLactationCategory": "ChildBearingAge",
              "Code": "Sample Code text.",
              "AlternateDrugs": [
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-01"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                },
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-02"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                }
              ],
              "Description": "Sample Description text.",
              "Trimester": "First",
              "MonographSectionId": 12,
              "InfoMessage": "Sample InfoMessage text."
            },
            {
              "PregnancyAndLactationCategory": "ChildBearingAge",
              "Code": "Sample Code text.",
              "AlternateDrugs": [
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-04"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                },
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-05"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                }
              ],
              "Description": "Sample Description text.",
              "Trimester": "First",
              "MonographSectionId": 15,
              "InfoMessage": "Sample InfoMessage text."
            }
          ],
          "InfoMessage": "Sample InfoMessage text."
        }
      ],
      "InfoMessage": "Sample InfoMessage text."
    },
    {
      "Diagnosis": {
        "ConditionId": {
          "IdType": "ICD10",
          "Id": "123ABC16"
        },
        "Description": "Sample Description text.",
        "InfoMessage": "Sample InfoMessage text.",
        "LevelsOfEvidence": [
          {
            "Recommended": true,
            "StrengthOfRecommendation": "EquivocalWeakAgainst",
            "Rating": "VeryLow",
            "ErrorMessage": "Sample ErrorMessage text."
          },
          {
            "Recommended": true,
            "StrengthOfRecommendation": "EquivocalWeakAgainst",
            "Rating": "VeryLow",
            "ErrorMessage": "Sample ErrorMessage text."
          }
        ]
      },
      "Drugs": [
        {
          "Drug": {
            "DrugId": {
              "IdType": "NDC11",
              "Id": "12345-6789-08"
            },
            "Name": "Sample Name text.",
            "LevelsOfEvidence": [
              {
                "Recommended": true,
                "StrengthOfRecommendation": "EquivocalWeakAgainst",
                "Rating": "VeryLow",
                "ErrorMessage": "Sample ErrorMessage text."
              },
              {
                "Recommended": true,
                "StrengthOfRecommendation": "EquivocalWeakAgainst",
                "Rating": "VeryLow",
                "ErrorMessage": "Sample ErrorMessage text."
              }
            ],
            "Message": "Sample Message text."
          },
          "Ratings": [
            {
              "PregnancyAndLactationCategory": "ChildBearingAge",
              "Code": "Sample Code text.",
              "AlternateDrugs": [
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-00"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                },
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-01"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                }
              ],
              "Description": "Sample Description text.",
              "Trimester": "First",
              "MonographSectionId": 20,
              "InfoMessage": "Sample InfoMessage text."
            },
            {
              "PregnancyAndLactationCategory": "ChildBearingAge",
              "Code": "Sample Code text.",
              "AlternateDrugs": [
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-03"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                },
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-04"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                }
              ],
              "Description": "Sample Description text.",
              "Trimester": "First",
              "MonographSectionId": 23,
              "InfoMessage": "Sample InfoMessage text."
            }
          ],
          "InfoMessage": "Sample InfoMessage text."
        },
        {
          "Drug": {
            "DrugId": {
              "IdType": "NDC11",
              "Id": "12345-6789-06"
            },
            "Name": "Sample Name text.",
            "LevelsOfEvidence": [
              {
                "Recommended": true,
                "StrengthOfRecommendation": "EquivocalWeakAgainst",
                "Rating": "VeryLow",
                "ErrorMessage": "Sample ErrorMessage text."
              },
              {
                "Recommended": true,
                "StrengthOfRecommendation": "EquivocalWeakAgainst",
                "Rating": "VeryLow",
                "ErrorMessage": "Sample ErrorMessage text."
              }
            ],
            "Message": "Sample Message text."
          },
          "Ratings": [
            {
              "PregnancyAndLactationCategory": "ChildBearingAge",
              "Code": "Sample Code text.",
              "AlternateDrugs": [
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-07"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                },
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-08"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                }
              ],
              "Description": "Sample Description text.",
              "Trimester": "First",
              "MonographSectionId": 27,
              "InfoMessage": "Sample InfoMessage text."
            },
            {
              "PregnancyAndLactationCategory": "ChildBearingAge",
              "Code": "Sample Code text.",
              "AlternateDrugs": [
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-01"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                },
                {
                  "DrugId": {
                    "IdType": "NDC11",
                    "Id": "12345-6789-02"
                  },
                  "Name": "Sample Name text.",
                  "LevelsOfEvidence": [
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    },
                    {
                      "Recommended": true,
                      "StrengthOfRecommendation": "EquivocalWeakAgainst",
                      "Rating": "VeryLow",
                      "ErrorMessage": "Sample ErrorMessage text."
                    }
                  ],
                  "Message": "Sample Message text."
                }
              ],
              "Description": "Sample Description text.",
              "Trimester": "First",
              "MonographSectionId": 30,
              "InfoMessage": "Sample InfoMessage text."
            }
          ],
          "InfoMessage": "Sample InfoMessage text."
        }
      ],
      "InfoMessage": "Sample InfoMessage text."
    }
  ]
}